Liver abscess caused by Klebsiella pneumoniae in a diabetic patient

the association may be explained if vasopressin degradation products retain their pressor activity but lose their antidiuretic activity. Another theory proposes that decreased vasopressinase metabolism due to pre-existent liver disease results in increased vasopressinase activity and increased vasopressin degradation. Patients with DI need access to fluids containing free water. The oral intake of pregnant women is restricted in most obstetric departments, which makes intravenous fluid management essential. Because of their inability to concentrate urine, patients cannot prevent hyperosmolality without the administration of high amounts of free water. LDDV, a vasopressin analogue with a different amino terminal that makes it resistant to vasopressinase, may be administered. No maternal or fetal adverse effects of LDDV have been reported during pregnancy. Moreover, LDDV has no pressor effect, which is important because of the association of DI with preeclampsia.